Response surface methodology for optimization of production of lovastatin by solid state fermentation
نویسندگان
چکیده
منابع مشابه
Response surface methodology for optimization of production of lovastatin by solid state fermentation
Lovastatin, an inhibitor of HMG-CoA reductase, was produced by solid state fermentation (SSF) using a strain of Aspergillus terreus UV 1718. Different solid substrates and various combinations thereof were evaluated for lovastatin production. Wheat bran supported the maximum production (1458 ± 46 µg g(-1) DFM) of lovastatin. Response surface methodology (RSM) was applied to optimize the medium ...
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ژورنال
عنوان ژورنال: Brazilian Journal of Microbiology
سال: 2010
ISSN: 1517-8382
DOI: 10.1590/s1517-83822010000100024